Temporal Constraints on Experimental Emmetropization in Infant Monkeys

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Temporal constraints on experimental emmetropization in infant monkeys.

PURPOSE To characterize the temporal integration properties of the emmetropization process, the authors investigated the effects of brief daily interruptions of lens wear on the ocular compensation for negative lenses in infant rhesus monkeys. METHODS Eighteen monkeys wore -3 D lenses binocularly starting from approximately 3 weeks of age. Six of these monkeys wore the lenses continuously. Fo...

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Effects of optically imposed astigmatism on emmetropization in infant monkeys.

PURPOSE Although astigmatism is prevalent during early infancy, the influence of astigmatism on early refractive development is unclear. This study was undertaken to determine the effects of astigmatism on emmetropization in monkeys. METHODS Infant rhesus monkeys (n = 39) were exposed to optically simulated astigmatism in one or both eyes from approximately 1 to 4 months of age. With-the-rule...

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Effects of photorefractive keratectomy-induced defocus on emmetropization of infant rhesus monkeys.

PURPOSE To investigate whether photorefractive keratectomy (PRK) performed in infant primates can modify emmetropization and therefore could be used to study mechanisms of refractive error development. METHODS Six healthy rhesus monkeys ranging in age from 2 to 3 months were randomly divided into two groups (n = 3 each). Anisometropia was induced in each animal by performing PRK on one eye. H...

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The Effects of the Relative Strength of Simultaneous Competing Defocus Signals on Emmetropization in Infant Rhesus Monkeys

PURPOSE We investigated how the relative surface area devoted to the more positive-powered component in dual-focus lenses influences emmetropization in rhesus monkeys. METHODS From 3 to 21 weeks of age, macaques were reared with binocular dual-focus spectacles. The treatment lenses had central 2-mm zones of zero-power and concentric annular zones that had alternating powers of either +3.0 dio...

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ژورنال

عنوان ژورنال: Investigative Opthalmology & Visual Science

سال: 2007

ISSN: 1552-5783

DOI: 10.1167/iovs.06-0743